A team of neurologists from UCLA and duPont Hospital for Children in Delaware found that voluntary exercise improves regeneration of neurons, both for those who work out, and for those recuperating after injury. The abstract in PNAS1 states:Recent advances in understanding the role of neurotrophins on activity-dependent plasticity have provided insight into how behavior can affect specific aspects of neuronal biology. We present evidence that voluntary exercise can prime adult dorsal root ganglion neurons for increased axonal regeneration through a neurotrophin-dependent mechanism. Dorsal root ganglion neurons showed an increase in neurite outgrowth when cultured from animals that had undergone 3 or 7 days of exercise compared with sedentary animals. Neurite length over 18-22 h in culture correlated directly with the distance that animals ran. The exercise-conditioned animals also showed enhanced regrowth of axons after an in vivo nerve crush injury. Sensory ganglia from the 3- and 7-day-exercised animals contained higher brain-derived neurotrophic factor, neurotrophin 3, synapsin I, and GAP43 mRNA levels than those from sedentary animals. Consistent with the rise in brain-derived neurotrophic factor and neurotrophin 3 during exercise, the increased growth potential of the exercise-conditioned animals required activation of the neurotrophin signaling in vivo during the exercise period but did not require new mRNA synthesis in culture.1Molteni et al., “Voluntary exercise increases axonal regeneration from sensory neurons,” Proceedings of the National Academy of Sciences USA, 10.1073/pnas.0401443101.Couch potatoing can’t be good for you. Use it and improve it. The discovery that neurons can be regenerated should be good news for those who have suffered injury. Physical therapy may be painful, but it offers hope. Grin and bear it for as long as it takes. Hopefully you’ll be grinning more eventually.(Visited 12 times, 1 visits today)FacebookTwitterPinterestSave分享0
A review analyzing clinical and observational research studies supports the use of low FODMAP diets in IBS treatment: “There is now high-quality evidence supporting the low FODMAP diet as a first-line therapy in IBS, demonstrating significant improvement in symptoms in 70% of all subtypes of IBS patients.”5In conclusion, low FODMAP diets show promise in diminishing IBS symptoms. Patients should be assisted by a nutrition professional during the elimination and challenge phases of the FODMAP diet. Different foods will precipitate symptoms in IBS patients and therefore, the diet must be individualized.Bibliography: 1. Low FODMAP Diet. Stanfordhealthcare.org. https://stanfordhealthcare.org/medical-treatments/l/low-fodmap-diet.html. Published 2018. Accessed December 1, 2018.2. Mahan L, Raymond J. Krause’s Food & The Nutrition Care Process. 14th ed. [Philadelphia, Pa.]: Saunders; 2017:546-548.3. Halmos E, Power V, Shepherd S, Gibson P, Muir J. A Diet Low in FODMAPs Reduces Symptoms of Irritable Bowel Syndrome. Gastroenterology. 2014;146(1):67-75.e5. doi:10.1053/j.gastro.2013.09.0464. Pedersen N, Felding M, Ankersen D, Vegh Z, Burisch J, Munkholm P. Low FODMAP diet reduces irritable bowel symptoms and improves quality of life in patients with inflammatory bowel disease in a randomized controlled trial. Journal of Crohn’s and Colitis. 2014;8:S47. doi:10.1016/s1873-9946(14)60092-15. Manning L, Biesiekierski J. Use of dietary interventions for functional gastrointestinal disorders. Curr Opin Pharmacol. 2018;43:132-138. doi:10.1016/j.coph.2018.09.003 By: Annabelle Shaffer, Dietetics senior at University of Illinois Urbana-ChampaignWhat is it? To begin, FODMAP stands for fermentable oligosaccharides, disaccharides, monosaccharides, and polyols. These are types of carbohydrates that can be found in common food items, such as honey, dairy, onion, and garlic1. Once in the gut, these carbohydrates may be improperly absorbed leading to fermentation by the bacteria, or microbiota, naturally found in your gut1. Individuals who suffer from Irritable Bowel Syndrome (IBS) experience gas, bloating, cramping, and changes in stool frequency or form after eating a large amount of foods containing FODMAPs1. IBS is diagnosed by a physician specializing in gastroenterology.A FODMAP diet is a diet low in fructose, fructans, galactans, lactose, and polyols2. Fructose can be found in apples, honey, sugar snap peas, watermelon, and mango. Fructans and galactans can be found in wheat products, legumes, and cashews. Lactose is found in varying amounts in all dairy products. Polyols are in apricots, mushrooms, as well as sugar alternatives such as xylitol and sorbitol.FODMAP diets are not intended to be lifelong. Instead, with advisement from a healthcare professional, you would eliminate all high FODMAP containing foods and eat low FODMAP alternatives for 6-8 weeks2. After the elimination period, the patient begins the challenge phase2. In this phase, the patient adds FODMAP foods back into their diet one at a time and identifies any foods that precipitate symptoms2.Who can benefit? The FODMAP diet was developed by researchers at Monash University in Australia to ease the symptoms of IBS. Since the diet’s creation, studies have been done on the efficacy of a low FODMAP diet in IBS symptom reduction. Thus far, the research is promising:A controlled cross-over study found that low FODMAP diets reduced IBS symptoms in comparison to the study population’s typical diet: “The results of this study provide high-quality evidence that the low FODMAP diet is efficacious for treatment of functional gastrointestinal symptoms in unselected IBS with symptoms being halved compared with a typical Australian diet.”3 A randomized control study also concluded a low FODMAP diet was successful in IBS symptom reduction: “A low-FODMAP diet reduced IBS-like symptoms and increased quality of life in patients with IBD in remission.”4
As India gets ready to celebrate the 70th year of Independence, in Pune, the house where Gopal Krishna Gokhale, one of the prominent leaders of the freedom movement, lived, is being converted into a museum. What is the project?The century-old red-tiled house stands on the campus of the Gokhale Institute of Politics and Economics (GIPE). Gokhale lived in Deccan House, which is now under renovation, between 1907 and 1915. The idea to convert Gokhale’s graceful single-storey house into a museum gained traction in 2015-16, the former year marking his death centenary while the latter marking his sesquicentennial birth anniversary. The Heritage Cell of the Pune Municipal Corporation began restoration and renovation work on the residence a few months ago, after the civic body furnished a grant of ₹25 lakh last year. The house will also be included in Pune’s heritage tour circuit. The project is being conceived on the lines of Mahatma Phule’s house in the city, which too has been converted into a museum, showcasing the great reformer’s life and times.What will it showcase?The museum will exhibit extensive memorabilia, including mementos and utility objects used by Gokhale, like his famous turban, his awards and his personal belongings, including his books. The home currently houses hundreds of photographs from the era, showcasing Gokhale’s life and milieu. Significant portions of his voluminous correspondence, through which the public and tourists can glean insights into his literary and political associations, are expected to be archived soon. In addition, there is a plan to digitise his papers and documents for public access, with the objective of delineating Gokhale’s political thought. His speeches and writings on economics will also be showcased.What is the significance?His descendants say the essence of the project is a bid to keep Gokhale’s ideas relevant. Among the great nationalists, Gokhale believed in the reforming power of Western institutions. The project also includes seminars and talks on Gokhale in Pakistan and Bangladesh.What are the other museums?Pune has had a tradition of transforming the homes of great historical figures into museums. The last days of the great Maratha military leader Mahadji Scindia, who died in Wanowrie, is immortalised in the magnificent ‘Shinde Chhatri’ — a three-storied samadhi in the Rajput architectural style, which is among Pune’s most recognisable landmarks. Social reformer Mahatma Phule’s 19th century house in the city’s teeming Ganj Peth area was transformed into a museum, where the great liberator of untouchables and backward communities lived since 1852 along with his equally renowned wife, Savitribai. The wada languished in a dilapidated state until 1993 when it was restored and renovated by an initiative taken by the civic body in a bid to capture the socio-political milieu of reform in the State in the mid-nineteenth century.Where is the Gandhi museum?Similarly, the halls of Aga Khan palace are renowned for the Gandhi museum today and as the place where Mahatma Gandhi and his wife, Kasturba, along with Gandhi’s secretary Mahadev Desai and Sarojini Naidu were imprisoned during the ‘Quit India’ movement in 1942. Declared as a monument of national importance by the ASI, the palace houses the memorials of the Mahatma and his wife while containing the samadhis of Kasturba Gandhi and Desai, who died in captivity.
The BJP government in Tripura would soon consult educationists to explore the possibility of introducing the NCERT syllabus at school level in the State without the “modifications made during the previous Left rule”, a Minister said on Wednesday.State Education Minister Ratan Lal Nath said, “The NCERT course, with a lot of modifications, was introduced during the Left rule, as a result of which students from Tripura were facing tough situation in all-India competitive examinations. Despite good results they were not getting government jobs as expected. So, we have decided to consult acclaimed educationists to introduce the syllabus at school level without change.”The Minister alleged that due to modifications in the syllabi, names of many great Indians were deleted and the names of many others were included, which were not desirable.“I do not want controversy, so I would not mention whose names were deleted and whose names were included. I think if the syllabi is introduced in its original form, everything would be corrected,” Mr. Nath said.To a question, he said there is a provision for 10% modification in the NCERT course to introduce local (State) history and geography, and those would be included.Tripura has a literacy rate of 97%.
About the authorPaul VegasShare the loveHave your say Ranieri slams Fulham: No desire. No passionby Paul Vegas10 months agoSend to a friendShare the loveOldham Athletic have dumped Fulham out of the FA Cup.Aleksandar Mitrovic missed a hotly-contested penalty as Fulham were dumped out of the FA Cup 2-1 by League Two side Oldham.Callum Lang headed in the visitors’ 89th-minute winner to stun the Premier League hosts and prompt extended touchline celebrations from caretaker boss and lifelong supporter Pete Wild.Denis Odoi’s goal early in the second half meant Fulham were expecting to coast home, only for Oldham to turn the tide as Bournemouth loan striker Sam Surridge equalised from the penalty spotAnd then Lang buried Gevaro Nepomuceno’s teasing cross, to spark exuberant celebrations on both the Oldham bench and among the delirious travelling supporters.Fulham boss Claudio Ranieri made six changes to the side beaten 4-1 by Arsenal in the Premier League five days earlier, but was “disappointed” his players did not seize their opportunity.”I gave a chance to them to show if I am right or wrong, to see if I am right to choose other players – I am right,” said Ranieri.”I did not see desire or passion, I wanted to see desire – show me I am wrong, show me! I am not wrong.”He added: “The first half was boring for us, the second half much better, we scored a goal and had chances to score, but then at the end they deserved to win. They made two goals, had another great chance and well done to them.”I am very disappointed, if we played as well as we play in the training session, we win the match. I don’t know what happened for these guys.”
Michigan senior midfielder Tyler Anderson (23) dribbles as OSU senior midfielder Yianni Sarris (6) pursues during a Nov. 9 match at Jesse Owens Memorial Stadium. OSU won, 1-0. Credit: Kelly Roderick / For The LanternFor the second time in five days, the Ohio State men’s soccer team bested its rival, this time to keep its season alive.OSU (9-6-4, 5-3-0) returned home to defeat Michigan (6-9-3, 3-3-2) in the quarterfinal round of the Big Ten tournament, 1-0, on Sunday.The victory came less than a week after the Buckeyes beat Michigan, 2-1, in Ann Arbor, Mich., to close the regular season.“I think we were just all really focused and really hungry to defend our home turf, and beat Michigan again twice in five days, obviously that was a really difficult task, but we embraced it and we ran with that,” redshirt-senior goalkeeper Alex Ivanov added.For the second consecutive game against the Wolverines, it was sophomore forward Danny Jensen who opened the scoring in the first half. The sophomore directed a header in front of the box off a high feed from senior midfielder Max Moller and deposited it into the corner of the net.“We knew exactly what they had, on the counter that they know exactly what we had,” Jensen said.The goal was Jensen’s fifth of the year, including his fourth in OSU’s last five games. However, Jensen said he is not the one responsible for the recent success.“My teammates are putting me in the right positions,” he said. “I’m not really doing too much. I just have to be in the right positions by moving a few yards, and they’re putting the ball on my head, on my foot.”Michigan appeared to tie the game with a header that got past Ivanov late in the first half, but the equalizer was waved off because of an offsides call.As a result, the first half came to a close with the Buckeyes holding a 1-0 lead. Michigan led in shots at the half, however, 5-3.But OSU turned that trend around to begin the latter half. In the first 30 minutes of the second half, the Buckeyes only allowed Michigan to get two shots off as they played a defensive, conservative style.“It was crucial that we kept focus and maintained our lead, and I think everyone just did really well to stay on the same page,” Ivanov said.Despite Michigan’s desperate search for the equalizer, the Buckeyes’ defense held strong, controlling possession for much of the second half and holding Michigan to only one shot on goal.“It was a great shutout today more than anything,” OSU coach John Bluem said. “We talked about at halftime, if we defended well, then we’ve already got the game won. If you don’t let them score, we won the game already, and I think that mindset helped.”It was the second-consecutive chippy game between the rivals. After 20 fouls were whistled in Wednesday’s contest, 37 were assessed Sunday – including two yellow cards in the final minute.“It’s an important game, they’re fighting for their season, we’re fighting for their season. It’s a rivalry, too,” Ivanov said about the number of fouls. “It’s always tough playing against Michigan, it’s pretty physical and demanding on the body.” Ivanov’s shutout was his seventh of the season and 15th of his collegiate career.Shortly after the game, Indiana defeated Northwestern in a penalty kick shootout to advance to the semifinals to meet the Buckeyes. OSU fell to Indiana on Oct. 12, 2-1.In College Park, Md., No. 1-seeded Maryland defeated Rutgers, 2-0, to earn the right to host the semifinals and championship as the highest remaining seed.Of the three other teams remaining in the tournament, OSU is 1-2-0 this season, allowing a combined five goals.However, Jensen said it would not be easy for future opponents to score many goals against the late-season iteration of the OSU defense.“Any team that is going to have to beat us, they’re going to have to score some great goals or we’re going to have to get unlucky, because we’re playing really well right now,” he said.OSU is set to travel to College Park, Md., to take on sixth-seeded Indiana in the semifinals Friday. That game is scheduled to kick off at 3:40 p.m.
Brutus Buckeye helps carry the flag spelling “Ohio” before the game against Purdue-Fort Wayne on Nov. 11. Ohio State won 107-61. Credit: Amal Saeed | Assistant Photo Editor
Croatia head coach Zlatko Dalic has criticized Cristiano Ronaldo after it was revealed that the Portuguese superstar was unhappy about missing out on the UEFA Men’s player of the year award.The award which was won by Ronaldo’s former teammate, Luka Modric who still represents Madrid has courted a lot of backlash and football super-agent Jorge Mendes criticized the decision to give it to the Croatian captain.The fact that Cristiano Ronaldo failed to attend Thursday’s UEFA gala to see his former teammate Luka Modric win the player of the year award has led to a heated debate in Croatia, one which national team coach Zlatko Dalic has commented on.Labelling the Juventus player as selfish, Dalic said he wouldn’t want to build a team around him.Vidic: “Ronaldo is the most professional footballer I’ve seen” Andrew Smyth – September 14, 2019 Nemanja Vidic opened up on how a 21-year-old Cristiano Ronaldo’s professionalism left him stunned at Manchester United.“Ronaldo is selfish and I’d never want him in my team,” he said in an interview with Sportske Novosti, as quoted by Marca.“He is the kind of player who thinks ‘even if we lose, the only thing that matters is that I score a goal.”As for Modric himself, the coach congratulated the player on the award and said that he is proud of how the midfielder hasn’t changed despite the fame and glory.
Barcelona president Josep Maria Bartomeu doesn’t expect Manchester United to sell Paul Pogba in January, but didn’t rule out making a move for himThe 2018 World Cup winner is understood to be considering his United future after another public spat with manager Jose Mourinho.The pair’s relationship has hit an all-time low after Mourinho stripped Pogba of the vice-captaincy and they were seen arguing with each other in a training session last week.Both Juventus and Barcelona have been linked with a move for the unsettled Pogba, but Bartomeu suggested that rumours of an impending exit for the French midfielder are unlikely.Juventus confirm Mario Mandzukic could leave this month Andrew Smyth – September 14, 2019 Sporting director Fabio Paratici confirmed reports that Mario Mandzukic could leave Juventus for a move to an unnamed Qatari team.“I read these rumours – not just Pogba but a lot of players. Most of the teams don’t want to sell their players. They want to grow,” Bartomeu told The Times.“When you hear from agents that a certain player is on the market – and I am not saying that about this player, but generally – I will sometimes call the CEO and say ‘Is it true you want to sell this player?’.“Usually, they say ‘No way, not for sale’ and that’s the end of it.”
Budget cuts hurt, but necessary says TCI Deputy Premier in parliamentary debate on hurricane funds Minister of Works puts government buildings reconstruction post hurricanes at $8.6m Facebook Twitter Google+LinkedInPinterestWhatsApp TCI Premier blasts Opposition side for “slop” information, sets it straight in HOA Facebook Twitter Google+LinkedInPinterestWhatsAppProvidenciales, 08 Sept 2015 – The Miss Teen Turks and Caicos Organisation, and Contestants, paid a courtesy call on the Rt. Hon. Robert Hall, Speaker of the House, in August at the House of Assembly. The occasion marked the first time any of the six contestants or the accompanying committee members had ever visited the House of Assembly. Hon. Hall gave the group a detailed history of parliament and the roles and functions of government in the Turks and Caicos Islands. The contestants also received a brief lesson on table and social etiquette. A courtesy call was also made to the Grand Turk Cruise Center where they were greeted by Mary Fulford, the 1st Miss Teen Turks and Caicos 2014/15. Together they welcomed visitors, and encouraged them to return and see as much of 40 islands and cays in the TCI as possible. The 2nd Annual Miss Teen Turks and Caicos pageant is slated for September 26, 2015 in Providenciales, to coincide with activities planned for this year’s National Youth Day. The lucky teen queen will win a myriad of prizes and will also participate in the 2016 edition of Miss Teen Universe to be held in Costa Rica. Recommended for you Related Items:grand turk cruise center, house of assembly, mary fulford, miss teen turks and caicos, robert hall